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Day 1 - references from the presentations

The following references from the presentations are in the order as in the VET 2016 conference programme for Day 1, and also available to download [PDF 349 KB]

Conference programme for Day 1 (PDF 17 KB), Day 2 (PDF 19 KB), Day 3 (PDF 15 KB)

References from Day 2

References from Day 3

References from all the presentations

Steve Budsberg & David Church - Can practice-based evidence complement and promote EBVM?

Nutting, P.A. and Stange, K.C. (2001) Practice-based research: The opportunity to create a learning discipline. In: Rakel, R. E. (ed) Textbook of family practice. Sixth ed. London: Saunders

Gordon-Evans, W.J. et al. (2013) Comparison of lateral fabellar suture and tibial plateau leveling osteotomy techniques for treatment of dogs with cruciate ligament disease. Journal of the American Veterinary Medical Association, 243(5), pp. 675-680. DOI: 10.2460/javma.243.5.675

Green, L.W. (2001) From research to “best practices” in other settings and populations. American Journal of Health Behavior, 25(3), pp. 165-178. DOI:

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Sebastian Arlt - Staircase of Evidence

EBVM Learning [Accessed 21/12/2016]

Oxford Centre for Evidence-based Medicine – Levels of evidence (March 2009) [online]. Available from: [Accessed 24 November 2016]

Cardwell, J. M. (2008) An overview of study design. Journal of Small Animal Practice, 49(5), pp. 217-218. DOI: 10.1111/j.1748-5827.2008.00594.x

Daly, J. et al. (2007) A hierarchy of evidence for assessing qualitative health research. Journal of Clinical Epidemiology, 60(1), pp. 43-49. DOI:

Holmes, M. A. (2007) Evaluation of the evidence. Veterinary Clinics of North America: Small Animal Practice,37(3), pp. 447-462. DOI:

Kochevar, D.and Fajt, V. (2006) Evidence-based decision making in small animal therapeutics. Veterinary Clinics of North America: Small Animal Practice, 36(5), pp. 943-959. DOI:

Sargeant, J. M.; Kelton, D. F. and O'Connor, A. M. (2014) Study designs and systematic reviews of interventions: building evidence across study designs. Zoonoses and Public Health, 61(S1), pp.10-17. DOI:

Achterberg, C., McDonnell, E. and Bagby, R. (1994) How to put the Food Guide Pyramid into practice. Journal of the American Diet Association, 94(9), pp. 1030-1035. DOI:

Davis, C.A., Britten, P. and Myers, E.F. (2001) Past, present, and future of the food guide pyramid. Journal of the American Diet Association, 101(8), pp. 881-885. DOI:

Diet, nutrition and the prevention of chronic diseases (2003) Report of the joint WHO/FAO expert consultation. WHO Technical Report Series, No. 916 (TRS 916). Geneva: World Health Organization

Arlt, S.and Heuwieser, W. (2016) The staircase of evidence – a new metaphor displaying the core principles of Evidence-based Veterinary Medicine [online]. Veterinary Evidence, 1(1). DOI: [Accessed 24 November 2016]

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Sandra Bertulat -Bacteriological examination of milk samples - the gold standard in mastitis diagnostic under evaluation

Bascom, S.S. and Young, A.J. (1998) A summary of the reasons why farmers cull cows. Journal of Dairy Science, 81(8), pp. 2299-2305. DOI:

Grohn, Y.T. et al. (1998) Effect of diseases on the culling of Holstein dairy cows in New York State. Journal of Dairy Science, 81(4), pp. 966-978. DOI:

Pitkala, A. et al. (2005) Interlaboratory proficiency testing as a tool for improving performance in laboratories diagnosing bovine mastitis. Journal of Dairy Science, 88(2), pp. 553-559. DOI:

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Constance White - Clinical decision-making and treatment patterns in canine prolapsed nictitans and feline herpetic keratitis

McClellan, M.B. et al. (2008) Evidence-based medicine and the changing nature of health care: Meeting summary (IOM Roundtable on Evidence-Based Medicine) [online] Washington: The National Academies Press. Available from: [Accessed 24 November 2016]

New CPD Opportunity: Using an evidence-based approach in you practice [Accessed 19 December 2016]

Centre for Evidence-based Veterinary Medicine [Accessed 21/12/2016]

BestBETs for Vets [Accessed 21/12/2016]

VetSRev - freely accessible online database of citations for systematic reviews [Accessed 21/12/2016]

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Alina Pohl - Efficacy of nonsteroidal antiinflammatory drugs for the treatment of acute puerperal metritis in dairy cow

Sheldon, M. et al. (2006) Defining postpartum uterine disease in cattle. Theriogenology, 65(8), pp. 1516-1530. DOI:

McLaughlin, C.L. et al. (2012) Evaluation of two doses of ceftiofur crystalline free acid sterile suspension for treatment of metritis in lactating dairy cows. Journal of Dairy Science, 95(8), pp. 4363-4371

Stojkov, J. et al. (2015) Assessment of visceral pain associated with metritis in dairy cows. Journal of Dairy Science, 98(8), pp. 5352-5361. DOI:

Pohl, A. et al. (2016) Randomized, controlled clinical trial on the efficacy of nonsteroidal antiinflammatory drugs for the treatment of acute puerperal metritis in dairy cows. Journal of Dairy Science, 99(10), pp. 8241-8249. DOI:

Silva Machado, V. et al. (2014) Subcutaneous immunization with inactivated bacterial components and purified protein of Escherichia coli, Fusobacterium necrophorum and Trueperella pyogenes prevents puerperal metritis in Holstein dairy cows. PLOS ONE, 9(3): e91734. DOI:10.1371/journal.pone.0091734 [Accessed 24 November 2016]

Pinedo, P.J. et al. (2015) Effect of intrauterine infusion of an organic-certified product on uterine health, survival, and fertility of dairy cows with toxic puerperal metritis. Journal of Dairy Science, 98(5), pp. 3120-3132. DOI:

Deng, Q. et al. (2015) Intravaginal lactic acid bacteria modulated local and systemic immune responses and lowered the incidence of uterine infections in periparturient dairy cows. PLOS ONE 10(4): e0124167. DOI:10.1371/journal.pone.0124167 [Accessed 24 November 2016]

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Merel Ritskes-Hoitinga - Systematic reviews of laboratory animal studies

Ritskes-Hoitinga, M. and Beynen, A.C. (1988) Atherosclerosis in the rat. Artery, 16(1), pp. 25-50

Russell, W.M.S. and Burch, R.L. (1959) The principles of humane experimental technique. London: Methuen & Co.

Norecopa 3R-guide [online] Available from: [Accessed 24 November 2016]

SYstematic Review Centre for Laboratory animal Experimentation [Accessed 24 November 2016]

SYRCLE e-Learning Systematic Reviews [Accessed 24 November 2016]

Leenaars, M. et al. (2012) A step-by-step guide to systematically identify all relevant animal studies. Laboratory Animals, 46(1), pp. 24-31. DOI: 10.1258/la.2011.011087

Hooijmans, C.R. et al. (2010) Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed. Laboratory Animals, 44(3), pp. 170-175. DOI: 10.1258/la.2010.009117

De Vries, R.D.M. et al. (2011) A search filter for increasing the retrieval of animal studies in Embase. Laboratory Animals, 45(4), pp. 268-270. DOI: 10.1258/la.2011.011056

De Vries, R.B. et al. (2014) Updated version of the Embase search filter for animal studies. Laboratory Animals, 48(1):88. DOI: 10.1177/0023677213494374

Hooijmans, C.R., Leenaars, M. and Ritskes-Hoitinga, M. (2010) A gold standard publication checklist to improve the quality of animal studies, to fully integrate the The Rs, and to make systematic reviews more feasible. Alternatives to Laboratory Animals: ATLA, 38(2), pp. 167-182

Hooijmans, C.R. et al. (2014) SYRCLE’s risk of bias tool for animal studies [online] BMC Medical Research Methodology, 14:43.  Available from: DOI: 10.1186/1471-2288-14-43 [Accessed 25 November 2016]

de Vries, R.B.M. et al (2015) A protocol format for the preparation, registration and publication of systematic reviews of animal intervention studies. Evidence-based Preclinical Medicine, 2(1), pp. 1-9. DOI: 10.1002/ebm2.7

Hooijmans, C.R. et al. (2014) Meta-analyses of animal studies : an introduction of a valuable instrument to further improve healthcare. International Laboratory Animals Research Journal, 55(3), pp. 418-426. DOI: 10.1093/ilar/ilu042

van Drongelen, J. et al. (2012) Adaptive changes of mesenteric arteries in pregnancy: a meta-analysis. American Journal of Physiology. Heart and Circulatory Physiology, 303(6):H639-57. DOI: 10.1152/ajpheart.00617.2011

de Vries, R.B. et al. (2012) Reducing the number of laboratory animals used in tissue engineering research by restricting the variety of animal models. Articular cartilage tissue engineering as a case study. Tissue Engineering. Part B Reviews, 18(6), pp. 427-435. DOI: 10.1089/ten.TEB.2012.0059

Hooijmans, C.R. et al. (2015) A A systematic review and meta-analysis of the ability of analgesic drugs to reduce metastasis in experimental cancer models. Pain, 156(10), pp. 1835-1844. DOI: 10.1097/j.pain.0000000000000296.

Yauw, S.T. et al. (2015) Systematic review of experimental studies on intestinal anastomosis. The British Journal of Surgery, 102(7), pp. 726-734. DOI: 10.1002/bjs.9776.

Currie, G.L. et al. (2013) Animal models of bone cancer pain: systematic review and meta-analyses. Pain, 154(6), pp. 917-926. DOI: 10.1016/j.pain.2013.02.033

Public accountability lecture [Accessed 25 November 2016]

Brief van staatssecretaris EZ: verzoek afbouwschema dierproeven [Accessed 25 November 2016]

REWARD campaign [Accessed 25 November 2016]

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Claire Wylie - Collaboration as a key feature of equine evidence-based research: a laminitis case study

Wylie, Claire E. et al. (2011) Frequency of equine laminitis: a systematic review with quality appraisal of published evidence. The Veterinary Journal, 189(3), pp. 248-256. DOI:

Wylie, Claire E. et al. (2012) Risk factors for equine laminitis: a systematic review with quality appraisal of published evidence. The Veterinary Journal, 193(1), pp. 58-66. DOI:

Wylie, Claire E. et al. (2013)   Risk factors for equine laminitis: a case-control study conducted in veterinary-registered horses and ponies in Great Britain between 2009 and 2011. The Veterinary Journal, 198(1), pp. 57-69. DOI:

Wylie, C. E. et al. (2013) Cohort study of equine laminitis in Great Britain 2009–2011: estimation of disease frequency and description of clinical signs in 577 cases. Equine Veterinary Journal, 45(6), pp. 681-687. DOI:  

Wylie, C. E. et al. (2013) Demographics and management practices of horses and ponies in Great Britain: a cross-sectional study. Research in Veterinary Science, 95(2), pp. 410-417. DOI:

Wylie, C. E. et al. (2016) Decision-tree analysis of clinical data to aid diagnostic reasoning for equine laminitis: a cross-sectional study. Veterinary Record, 178(11), pp.1-8. DOI:

Ireland, J.L. et al. (2013) Preventive health care and owner-reported disease prevalence of horses and ponies in Great Britain. Research in Veterinary Science, 95(2), pp. 418-424. DOI:

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Andrea Jeffrey and Sue Badger - Don't be afraid to ask the question: a simple guide for veterinary nurses to conducting evidence-based research in clinical practice

EBVM Learning [Accessed 20 December 2016]

Centre for Evidence-based Veterinary Medicine [Accessed 25 November 2016]

Canadian Centre for Evidence-Based Nursing (CCEBN) [Accessed 20 December 2016]

Courtney, M. and McCutcheon, H. (eds) (2010) Using evidence to guide nursing practice. Second ed. London: Elsevier Saunders

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Clare Boulton - Finding the evidence

BestBETS for Vets [Accessed 20 December 2016]

VetSRev - freely accessible online database of citations for systematic reviews [Accessed 21/12/2016]

Veterinary Evidence [Accessed 20 December 2016]

Grindlay, D., Brennan, M.L. and Dean, R.S. (2012) Searching the veterinary literature: a comparison of the coverage of veterinary journals by nine bibliographic databases. Journal of Veterinary Medical  Education, 39(4), pp. 404-412. DOI:

RCVS Knowledge EBVM Toolkit [Accessed 20 December 2016]

EBVM Learning [Accessed 20 December 2016]

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